Dear all,
Could you explain two terms of "Accessible Surface Area"(ASA) and
"Buried Surface Area"(BSA) of PISA at EBI ?
I thought that
Standard accessible surface area =
Solvent accessible surface area + Buried surface area.
When I looked up the result of PISA, ASA is always bigger than BSA
except "inaccessible residues". Thus, I think that ASA of PISA means
that "Standard accessible surface area" but one weird thing is that
those values of same type residues,i.e. Ala, are quite varied among one
chain.
Also, "Inaccessible residues" has 0.00 square angstrom for both ASA and
BSA. How can this happen? I believe that ASA should be bigger than 0.00,
for instance, 100 angstrom square.
Best,
Hyunchul Kim
Ph.D candidate
Bioinformatics program
Keio University, Japan
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