Hello,
We are trying to refine a structure using REFMAC and we are facing problem in
refining the double conformations of a cysteine residue. One conformation is
involved in formation of a disulfide linkage and other conformation is free. Is
there any way to define the restraints so that both the conformations can be
refined.
With kind regards,
Prasenjit
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Prasenjit Bhaumik, Ph.D.
Protein Structure Section
Macromolecular Crystallography Laboratory
National Cancer Institute at Frederick
1050 Boyles Street, Building-539, Room-145
P.O. Box B, Frederick,
MD-21702, USA
Phone: 301-846-1974, Fax: 301-846-7101
E-mail: [log in to unmask]
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