Postdoctoral associate in RNA Structural Biochemistry

Introduction:
The Department of Cell and Molecular biology (CMB) at the Karolinska  
Institutet in Stockholm is strongly focused on basic science  
conducting research in several areas of cell, molecular, and  
developmental biology. CMB is comprised of more than 20 independent  
research groups organized in five themes: Molecular Cell Biology,  
Developmental and Stem Cell Biology, Gene Regulation, Genome  
Structure and Integrity and Infection and Cancer. The group of Martin  
Hallberg - belonging to the theme of Molecular Cell Biology - apply X- 
ray crystallography, electron microscopy and biochemistry to  
understand tRNA processing, modification and transport.

Research description:
Transfer RNAs (tRNAs) must be recognised by the correct aminoacyl- 
tRNA synthase, by elongation factors and by elements on the ribosome  
to deliver their valued amino-acid cargo to the growing peptide chain  
through the action of the ribosome. In all kingdoms of life,  
mechanisms are in place to ensure the fidelity and efficiency of tRNA  
function. We aim to understand the structural basis of tRNA  
maturation and transport by studying the molecular structure of  
proteins - both with and without target RNA – that are involved in  
processing, modification and nucle-cytoplasmatic transport of tRNA.

Successful candidates will participate in all steps involved in  
structure determination of target proteins and target RNA/protein  
complexes.

Suitable candidates have a PhD in a relevant area, preferably in RNA  
Biochemistry, Structural Biology or closely related subjects. A  
general requirement to be eligible for this position is a doctoral  
degree from a University outside Sweden.

The position is offered for two years (full-time) and is funded by a  
non-taxable scholarship.

Last date for applications is July 18 (2007). Please, use reference  
“Dnr 2966/2007”.

The application should contain a cover letter and a CV with  
publication list. Names and emails of two references should be also  
provided.

Application sent to:
Att: Martin Hallberg Dnr 2966/2007
CMB
Medical Nobel Institute
Karolinska Institutet
Box 285
171 77 Stockholm
Sweden

or through email:  [log in to unmask]

Please see: http://jobb.ki.se/external/ad/showAd.asp?adId=1285

.
B. Martin Hallberg, PhD
Assistant professor
Department of Cell and Molecular Biology
Medical Nobel Institute
Karolinska Institutet
Nobels väg 3 (visiting address)
SE-171 77 Stockholm
Sweden