A three date short course "Genetic Association Studies and Mendelian-
Randomisation will take place in the Department of Social Medicne,
Unviersity of Bristol from 11th-13th July 2007.
For more information and etails of how to book
http://www.epi.bris.ac.uk/shortc/genetics.htm#mendel
Tutors: Professor George Davey Smith and Dr Sarah Lewis (organisers), Dr
Ian Day, Dr Tom Gaunt, Dr Philip Guthrie, Professor Debbie Lawlor,
Professor Lyle Palmer, Dr Santiago Rodriguez and others.
Please see revised details of this course.
Who the course is intended for: The course is designed for medical
researchers who already have an understanding of epidemiological concepts
and methods. Participants should have at least a basic knowledge of
statistics, and genetics knowledge at least to the level of our Genetics
for Epidemiologists Short Course.
Course content: Topics to be covered include: Study design, statistical
analysis, confounding by population structure, indirect associations-
linkage disequilibrium, haplotypes, population heterogeneity, replication
of findings and sample size issues, meta-analysis, biobanks, candidate
gene versus whole genome association approach, interpreting results,
detecting and minimizing genotyping error, introduction to Mendelian
randomization, types of inference in Mendelian randomization, limitations
of Mendelian randomization, future of genetics in public health.
Suggested pre-course reading: Cordell HJ and Clayton DG. Genetic
association studies. Lancet 2005;1121-31.
Hattersley AT and McCarthy MI. What makes a good genetic association
study? Lancet 2005;1315-23.
Davey Smith G, Ebrahim S. "Mendelian randomization": Can genetic
epidemiology contribute to understanding environmental determinants of
disease? Int J Epidemiol 2003;32:1-22.
Teaching time: Eighteen hours with formal lectures, practical sessions,
and group discussion work.
Course fee: £450.
You can either pay over the phone by credit card or we will send you an
invoice which must be paid according to our terms and conditions.
For further information: please contact [log in to unmask]
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