Hi,
I would like to ask if using default templates and parameters (following the documentation) is the recommended approach for doing gray and white matter brain volumetry with SPM5,
or if any other set of parameters is known to generally optimise this procedure. Details:
"A rigid-body rotation and translation was first performed
on all subjects using the coregister function in SPM5, and the SPM5 T1
template as the reference image. All subjects were then segmented using the default
templates and parameters for this version. Specifically, these parameters included
2 Gaussians each for WM, GM, and CSF and 4 Gaussians for everything not fitting
these categories, a warping regularization value of 1, a warp frequency cutoff
of 25, very light regularization (0.0001), a 60mm cutoff for the full width at half
7 maximum (FWHM) of Gaussian smoothness of bias, and a sampling distance of 3."
Frederick Klauschen
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