I would also have to put in a vote for POPS if you know the protease
specificity well. You can input everything you know about primary
structure specificity (not secondary or tertiary) and search whole
proteomes for cut sites or just your favorite protein (cut and paste
sequence).
http://pops.csse.monash.edu.au/pops.html
On Fri, 6 Apr 2007, William Scott wrote:
> Date: Fri, 6 Apr 2007 14:30:19 -0700
> From: William Scott <[log in to unmask]>
> To: [log in to unmask]
> Subject: [ccp4bb] Summary: [ccp4bb] predicting protease cleavage sites in
> proteins?
>
> Thanks, everyone!
>
> This was a very popular answer: http://us.expasy.org/tools/peptidecutter/
>
> also
>
> http://www.cbs.dtu.dk/services/NetCorona/
> http://www.cbs.dtu.dk/services/NetPicoRNA/
>
> and
>
> If you are interested in the physiological, known cleavage sites, you
> may also try one of the possible searches at the MEROPS database:
>
> http://merops.sanger.ac.uk/cgi-bin/show_substrate
>
>
> I asked this on behalf of my wife; hence the British sarcasm:
>
> Begin forwarded message:
>
>> It was really helpful thank you. Ironic that you get answers from all over
>> the world instantly when in two weeks I can't get a response from any of
>> the geniuses here.
>
>
> Again, thanks.
>
> Bill
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