A programme is now available for the
EMBO Workshop on THE CHEMISTRY AND BIOCHEMISTRY OF CATALYSIS BY BIOLOGICAL
SYSTEMS - 20 - 22 June 2007, EMBL Hamburg
Please visit our website for workshop and registration details:
http://www.embl-hamburg.de/workshops/2007/catalysis/
or contact: [log in to unmask]
Registration deadline: 31st March 2007
The number of participants is limited to 100.
Posters will be on display throughout the meeting.
A number of presentations will be selected from poster abstracts.
Workshop aims:
With the continuously emerging new data from high throughput and genomics
initiatives, there is a strong need to optimally use the available
structural knowledge on enzymes. This concerns academic research itself as
well as bridging academic science and application directed research such as
drug design or biotechnology.
The aim of this workshop is to discuss the continuously developing means for
in-depth investigations of biocatalysts. The chemical and biochemical basis
for reaction mechanisms will be addressed on a wide range of enzymes.
Specific emphasis will be given to the use of structural information from
X-ray crystallography and complementary techniques for the elucidation of
structure function relationships of biocatalysts. Putting known approaches
in a new perspective will also be addressed. Sufficient time will be
allocated to specific problems such as inhibitor design and enzyme
engineering using the latest developments in the studies of transition state
analogues and on directed evolution approaches. The workshop will gather
specialists from a variety of areas in structural and chemical biology as
well as young post-doctoral researchers. The topics will cover X-ray
crystallography, NMR, biophysical methods such as ITC, spectroscopy and
kinetics (enzymology) as well as complementary organic chemistry approaches
and computational studies: quantum mechanics, molecular dynamics and in
silico docking. Each of these areas will address a specific set of
structural properties and the issue of how to best make use of the obtained
information.
The multidisciplinary program will provide an ideal framework for getting to
know the latest developments in this research field.
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