It depends - if it is a rotation axis then no - you will have symmetry
clashes, But if it is a screw axis thats OK..
Of course - you could have multiple conformations. You can have those
on a symmetry axis
Eleanor
..
Karolina Michalska wrote:
> Dear all,
>
> I have a 2A structure in C2 space group which is already refined quite
> well (R=0.194, Rfree=0.229). It is MR solution of the same protein but
> the crystal form is different. Everything seems to be OK apart from the
> density on a symmetry axis. The density is not very well defined but it
> seems to belong to the protein chain. Specifically, to the loop that is
> ordered in the model structure and fits also into this density. I cannot
> see any alternative conformation for this region. Does the protein chain
> on a symmetry axis make a physical sense? Or maybe I have something
> wrong here?
>
> Karolina
>
>
>
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