Dear Allstat,
Please find the details of our latest contract vacancy below:
**Pharmacometrician position within Clinical Pharmacology, Statistics
and PDM (Pharmacokinetics , Dynamics and Drug Metabolism)**
Successful candidate will be appropriately positioned in one of the
three groups constituting the pharmacometrics discipline depending on
core skill sets and interests. While core responsibilities and focus
varies across the groups, the operating environment promotes shared
delivery. The unified pharmacometrics goal is to improve drug
development efficiency by quantitatively linking preclinical models of
disease with clinical outcome through mechanistic approaches and
applying these models prospectively in decision-making and advanced
statistical study designs.
Responsibilities include the use of innovative analytical methods to
integrate knowledge of pharmacokinetics, pharmacodynamics,
characteristics and disease states to optimize doses, dosage regimens
and study designs. Responsibilities will include evaluating and applying
new techniques in PK/PD data analysis and /or advanced statistical study
design that improve information quality and utility, and enhance
productivity. You will also be responsible to educate Discovery and
Development colleagues in the role of these methods.
In addition to the site-specific activities the successful candidates
will forge collaborative relationships across all sites with partner
Pharmacometric groups, other subject matter specialists and groups
external to the organization (leading academics, Clinical Research
Organizations etc.). The successful candidate will work with colleagues
to ensure the client's position as a leader in the use of numerical
approaches supporting drug development strategies and worldwide
registration is maintained and enhanced.
Requirements: A doctorate degree or equivalent in pharmaceutical
sciences or statistics\mathematics or related discipline. Must have a
good mix of skills covering aspects from across at least some of the
following areas: design and analysis of pharmacokinetic and
pharmacodynamic studies, nonlinear mixed effects models, application of
mechanistic PK\PD models, disease progression modelling , meta-data
models utilising internal and external sources, strong statistical
skills, clinical trial design using principles of optimal design and
trial simulation and understanding of Bayesian theory in decision
theory/ trial design . Must also possess good skills or at least good
knowledge of specialist software, such as NONMEM, SAS, SPlus, Winbugs
and/or TS2 as well as good written and oral communication skills.
If you would like to discuss this position in detail, or for a
confidential consultation on all of our current Biostatistics and
Programming opportunities in the UK and Europe, please contact me
directly. Details of our current contract and permanent vacancies can
also be found at: http://www.jamesharvard.com/pharma/careers_browse.htm.
I look forward to hearing from you.
Kind Regards,
Chris Smith
Consultant ~ Biostatistics Division
James Harvard Pharmaceutical Ltd
T. +44 (0)20 7922 7137 M. +44 (0)7919 448334 F. +44 (0)20 7922
7101
E: [log in to unmask]
W: www.jamesharvardpharma.com
25 - 27 Wootton Street : Waterloo : London : SE1 8TG
For the latest Statistics and SAS Programming vacancies go to
http://www.jamesharvard.com/pharma/careers_browse.php
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