Finding the right dose: efficient statistical strategies
Medical and Pharmaceutical Statistics Research Unit
The University of Reading, UK
Thursday, 7 September 2006
Speakers
Dr Yinghui Zhou (MPS Research Unit, Reading)
Professor John O'Quigley (University of Lancaster)
Dr Pasi Korhonen (StatFinn OY))
Dr Adrian Mander (MRC - Human Nutrition Research)
Dr Mike Smith (Pfizer Global R & D)
Summary
Finding appropriate doses from early phase clinical trials is essential for efficient drug development. Conventional designs can take a long time to complete, and tend to concentrate effort at doses which are later rejected. They do not include formal procedures for deciding when to stop nor for making the final dose selection. Recently, adaptive designs have been proposed to speed up dose-finding procedures and to focus more exclusively on the target dose. In spite of the advances that have been made with this methodology, many important issues remain, including details of how to implement the methodology in practice. The aim of this symposium is to present recent advances and to discuss how to overcome problems that may arise in implementation.
Registration Fee (includes lunch and refreshments)
£85.00
£45.00 (academic/public sector rate)
Further details
http://www.rdg.ac.uk/mps/mps_home/symposium/symposium.htm
or contact
Barbara Dodds
MPS Research Unit
The University of Reading
PO Box 240
Earley Gate
Reading
RG6 6FN, UK
Tel: +44 118 378 6662
Fax: +44 118 975 3169
e-mail: [log in to unmask]
___________________________________________________
Patrick Kelly, PhD
Senior Research Fellow
Medical and Pharmaceutical Statistics Research Unit
The University of Reading
PO Box 240, Earley Gate
Reading, RG6 6FN, UK
Tel: +44 118 378 8916
Fax: +44 118 975 3169
Web: http://www.rdg.ac.uk/mps
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