Dear all,
I have been assigned to explore adaptive designs in two- arm or more
clinical trials.
I have done some research regarding adaptive designs in clinical trials,
however most of the papers are related to adaptive allocation of subjects.
I am mostly interest in papers related to designs where you can drop or add
(I am not sure if adding is possible) arms (groups) during the trial and
then adjust for the sample size. The only paper I have found until now
discussing these is one from Mr. Mark Chang “Adaptive Design for Clinical
Trials”.
Any references (papers or books) would be of much help.
Kind Regards,
Ioanna Gioni
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