Dear Colleagues,

On behalf of the International Society for Clinical Biostatistics as well as
on behalf of the Local Organising Committee and the Scientific Programme
Committee, we warmly invite you to

ISCB27         27th Annual Conference of the
               International Society for Clinical Biostatistics (ISCB) at

27-31 Aug 2006 Uni-Mail site of the University of Geneva
               Geneva, Switzerland


15 March 2006  Deadline for submission of abstracts and posters.
               Abstracts should be submitted preferably via
www.iscb2006.info.

15 June 2006   deadline early registration with reduced fee

The 27th Annual Conference in Geneva will provide a forum for the
international exchange of theory, methods and applications of biostatistics
in medical research and practice among clinicians, statisticians and members
of other disciplines, such as epidemiologists, clinical chemists and
clinical pharmacologists, working or interested in, the field of clinical
biostatistics. Selected and preferred topics to be discussed are

·       Sample sizes for clinical trials with continuous data
·       An introduction to the role and applicability of data mining in drug
development
·       Assessment of predictive performance by cross-validation and
bootstrapping, with applications to
          high dimensional data
·       The use of fractional polynomials in regression modelling
.       Adaptive designs: Looking for a needle in a haystack - a new
challenge in medical research
·       Competing risks in chronic disease management
·       Drug sensitivity and drug resistance
·       Regulatory affairs - Compliance or science?
·       Adaptive clinical trials
·       Subfertility statistics
·       Statistics in Dentistry: Methodological challenges in the analysis
of oral health data:
.         Split-mouth studies
·       Advanced variable selection and multivariable modelling
·       Robust statistical methods
·       WHO Statistics
·       Biomarker Identification and Validation
·       Bridging Studies
·       Building and Validating Prognostic Models and Clinical Prediction
Rules
·       Clinical Trials Registry Issues
·       Data Mining in Drug Development
·       E Trials: Data Capture, Data Quality, Data Review
·       Epidemiological Studies for Screening and Prevention
·       Meta analysis for Complex Problems in Clinical and Epidemiological
Research
·       Pharmacogenomics/proteomics Studies
·       Safety Analysis of Biologics (vaccines, transfusion products)
·       Simulation in Clinical Trials
·       Spatial Studies and Models

For the latest information, please see www.iscb2006.info