I am trying to clarify whether the x, y, z coordinates displayed when clicking 'volume' when the glass brains are displayed on a 'Results' page following the definition of a contrast are Talairach or MNI. The SPM99 manual (I know its an outdated version, but I'm working on old data) states that they are Talairach. However, can you explain the following from the manual regarding MNI:
• The space of the template images in SPM is based upon the Talairach system, but does
not make assumptions about brain symmetry, and includes the cerebellum.
• The stereotactic space is based on 152 brains from the Montréal Neurological Institute,
and will eventually be replaced in due course by a 450-brain version for the entire ICBM
consortium ().
• The 152 subject average brain was chosen rather than the MNI305 official standard brain
because from the 152 subjects T2- and PD-weighted images were also available, allowing
much more flexibility in the range of different MR contrasts that can be spatially
normalized to the same stereotaxic space. See spm_templates.man for details.
• A combination of templates may be used when the image to determine parameters from is
different (e.g., intensity with a new MRI sequence) from the templates provided by SPM.
For other purposes, e.g. normalising PET-ligand scans, creating a user-specified template
should be considered.
Please reply to all.
Much appreciated,
Julie E. McEntee, M.A.
Senior Research Program Coordinator
Department of Psychiatry- Neuroimaging
Johns Hopkins University School of Medicine
600 N. Wolfe St./ Phipps 316
Baltimore, MD 21287
Phone: 410-502-0468
Fax: 410-614-3676
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