LLN, le 6/03/02
Jeff,
I'm not totally sure, but the BrainVisa-Anatomist package may do some
of the things you're looking for. It works with Linux, MacOs and
Windows, is free and SPM compatible. Have a look at:
<http://brainvisa.info/>
Yours,
Mauro.
>Listmates,
>
>I'm in the process of deciding how to best implement a non-atlas based
>approach to analyzing our fMRI data, and I would like to learn from the
>experience of others as to which materials and methods would be best for
>our needs. Since the patient population for which we have fMRI data is
>fraught with the presence of brain atrophy (some quite significant), it
>doesn't seem appropriate to warp to a common SPM template. Rather, I
>would like to draw anatomically defined masks for particular regions of
>interest and examine the activity characteristics within these regions
>(e.g., ratio of activated voxels to total voxels, mean activation of
>voxels in ROI, etc.). The ROIs would also provide us the valuable data
>of accounting for volumetric differences in these regions among the
>subjects, which can then be used to correct for activity/atrophy
>interactions.
>
>What tracing software for the creation of anatomical masks best works
>with SPM2 or SPM5? And, does anyone know of a primer, good methods
>paper, or workshop for how to implement this anatomical ROI/non-atlas
>approach in SPM2 or SPM5?
>
>My previous SPM experience has been confined to normal anatomy, so what
>we're hoping to do is a bit foreign right now. I want to do the right
>thing with this data and warping to the SPM template doesn't seem to be
>it. I know manual tracing will be a major pain, but I don't see any
>other way to work around the atrophy/function issue.
>
>Regards,
>Jeff Browndyke
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______________________________________
Mauro PESENTI
Research Associate, National Fund for Scientific Research (Belgium)
Unite de Neurosciences Cognitives
Departement de Psychologie
Universite Catholique de Louvain
Place Cardinal Mercier, 10
B-1348 Louvain-la-Neuve
tel.: +32 (0)10 47 88 22
fax: +32 (0)10 47 37 74
E-mail: [log in to unmask]
http://www.nesc.ucl.ac.be
http://www.nesc.ucl.ac.be/mp/pesentiHomepage.htm
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