Gray matter density is definitely influenced by age. The obvious study is
Good et al. 2001, Neuroimage 14 p21-36
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11525331&query_hl=1).
We did a study of obstructive sleep apnea patients using smaller numbers
where we also found an effect of age independent of the group
(patient/control)
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12421746&query_hl=5)
Cheers,
Paul
On Sun, 4 Sep 2005 09:32:12 -0500, Moo K. Chung <[log in to unmask]> wrote:
>Dear SPMers,
>
>If anyone knows a previous study if the gray matter density value obtained
>in VBM will be influenced by age.
>In somewhat related note, how gray-white matter intensity contrast will
>changes as a function of age?
>Thanks in advance.
>
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