Dear Elaine,
I've done quite a bit of cortico-cortical tracing within hemisphere with
Fdt and so far it seems to work well. By that I mean that I can usually
find paths that I believe should exist between two different cortical
regions. I often get false paths due to various artifacts (e.g. dti
resolution sometimes means that paths jump sulci), but with a little care,
it's generally easy to identify and stop such paths from happening.
Having said all that, we use 60 direction data and tend to average several
acquisitions to increase SNR. Also, I'm looking for fairly strong
paths. When I've looked for weaker ones, or ones penetrating larger fibre
bundles (e.g. the acoustic radiation), this often fails.
So in principle Fdt should be fine for cortico-cortical connections, but it
does depend heavily on the specific path(s) you're interested in and the
quality of the data you have.
Cheers,
Joe
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Joseph T. Devlin, Ph. D.
FMRIB Centre, University of Oxford
Headley Way, Headington
Oxford, OX3 9DU, UK
Phone: +44-(0)1865-222-494
Fax: +44-(0)1865-222-494
Email: [log in to unmask]
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