UNIVERSITY OF OXFORD
Mathematical and Physical Sciences Division
DEPARTMENT OF STATISTICS
Postdoctoral Research Assistant(s): 2 Positions:
(1) Statistical Methods for the Analysis of Genome-Wide Association Studies (3 years)
(2) Statistical Methods for Geographical Population Structure in Genetic Studies (4 years)
Academic-related Research Staff Grade 1A: Salary £20,044 to £30,002 (bar) per annum
Two fixed-term research positions, both funded by the Wellcome Trust, are available to work in the research group of Professor Peter Donnelly, on statistical issues in modern genetic studies. The posts would commence on January 1, 2006, or at a different time by arrangement. Well-qualified successful applicants are likely to be appointed at or near the top of the salary scale given above.
The first post relates to the development, study, and application of novel statistical methods for genome-wide association studies for human diseases. Although the focus of the post is on methodological development, it is associated with the Wellcome Trust Case Control Consortium, a UK-wide collaboration which will perform large genome-wide association studies on eight common human diseases, and represents an exciting opportunity to be involved in one of the largest studies of its type internationally. Professor Donnelly chairs the consortium.
The second post concerns the development of statistical methods for inferring geographical population structure on the basis of genetic data, and how best to account for structure in genetic association studies. Again, the primary focus of the post is methodological, but it is associated with a large Wellcome Trust-funded study which will sample and genotype around 3,000 individuals to assess UK population structure empirically. There will be close involvement with the data generated by this project.
For the first post, candidates should have a strong background in modern statistics and its application. For the second post, a background in either modern statistics or statistical population genetics is necessary. Good computational skills are essential for both posts, and candidates should have, or expect soon to have, a doctorate. An existing background in genetics applications would be an advantage for both posts, but candidates wishing to move into the genetics field are also welcome to apply. The Department of Statistics in Oxford is one of the largest and strongest in the UK, and a world leader in statistical genetics.
Informal enquiries should be directed to [log in to unmask] Further particulars are available from http://www.stats.ox.ac.uk, or the address below.
Applications should comprise a curriculum vitae and a list of publications together with the names, addresses, telephone, fax and e-mail details of three referees. Applicants should make clear for which of the posts they are applying, or whether they wish to be considered for both posts.
Applications (7 copies, one copy for candidates outside the UK) should be submitted to Personnel Administration, Department of Statistics, 1 South Parks Road, Oxford, OX1 3TG. Applications faxed to +44 1865 272595 or e-mailed to [log in to unmask] are acceptable as long as they are followed by hard copy. Please always quote reference number: AM-05-012.
The closing date for applications is 8 November, 2005.
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