*/Short Course in FBAT/PBAT at /**/Harvard/**/ /**/School/**/ of Public
Health/*
*/
Course Date and Location: /*June 20-22, 2005 at the Harvard School of
Public Health, Boston MA.
*/Course Organizers and Faculty: /*Nan Laird, Christoph Lange, and Xin
Xu. Departments of Biostatistics and Environmental Health Sciences,
Harvard School of Public Health
*/Description/*:
The increasing availability of genetic marker data, especially SNP’s,
has made investigations of genetic associations between marker data and
disease commonplace. This course will focus on family based designs for
association studies; these designs use information on affected
individuals and their relatives, most commonly parents and/or siblings.
Family based designs are attractive in that they test for both
association and linkage and avoid difficulties with population
stratification and admixture. This course will give a very brief
introduction to the basic concepts of genetic association in general,
and family based designs in particular. The focus of the course is on
the FBAT/PBAT methodology and how to use the packages. The orientation
of the course is practical rather than theoretical. It combines lectures
and computer tutorials with hands on data analysis using the FBAT and
PBAT packages. Both packages can be accessed from the FBAT/PBAT web
pages http://www.biostat.harvard.edu/~clange/default.htm
<http://www.biostat.harvard.edu/%7Eclange/default.htm> and
http://www.biostat.harvard.edu/~fbat/default.html
<http://www.biostat.harvard.edu/%7Efbat/default.html> . A special
website will be created for the course so that all course materials will
be available there.
*/Intended audience/*: This course is intended for epidemiologists, data
analysts, geneticists, clinicians and statisticians involved in the
analysis of genetic data. Familiarity with genetic concepts as well as
background in basic statistics at the level of linear/logistic
regression is highly desirable. Participants are encouraged to bring
their own data sets; check the FBAT web page for details on file format.
We also strongly recommend that participants read the manuals before
attending the course. We will schedule a limited number of presentations
from course participants on their applied work in genetic association.
Participants interested in making a presentation should submit an
abstract for a short (20-30 minute) presentation.
*/Application, Registration and Fees./* The course fee is $350.00; this
covers course materials, two lunches, a course dinner and coffee breaks.
Applications will be accepted on a first come first serve basis; the
course is limited to 45 participants. Full time doctoral students may
obtain a reduced fee of $150 with a letter certifying student status
from your institution. Please fill out the Registration Form and return
via email to Jennifer Fitts ([log in to unmask]
<mailto:[log in to unmask]>_).
To download the course information and Registration Form, go to:
http://www.biostat.harvard.edu/~clange/default.htm
<http://www.biostat.harvard.edu/%7Eclange/default.htm>
or
http://www.biostat.harvard.edu/~fbat/default.html
<http://www.biostat.harvard.edu/%7Efbat/default.html>
*/Application Deadline:/* May 1, 2004.
*/ /*
*/Preliminary Schedule/*
Monday 6/20
8:00- 8:30 Registration
8:30-10:00 Basic concepts; the TDT and its generalization
10:00-10:15 Break
10:15-11:00 Examples/Guest Presentations
11:45-12:30 FBAT computer tutorial
12:30-1:30 Lunch
1:30- 3:00 Haplotypes, multiple phenotypes: FBAT-GEE
3:00- 3:15 Break
3:15- 3:45 Examples
3:45- 5:00 Computer tutorial/lab
6:00 Course dinner
Tuesday 6/21
8:30-10:00 Study Design Issues: Power and Sample Size; estimating the
effect size
10:00-10:15 Break
10:15-11:00 Guest presentations/examples
11:00-12:30 PBAT Computer tutorial
12:30- 1:30 Lunch
1:30- 3:00 Estimating the conditional mean model and screening
3:00- 3:15 Break
3:15- 3:45 Examples
3:45- 5:00 Computer tutorial/lab
Wednesday 6/22
8:30-10:00 More Examples, Guest Presentations
10:00-10:15 Break
10:15-11:45 Special/Advanced topics
11:45-12:30 More Examples, Computer lab
12:30-1:30 Lunch
*REGISTRATION FORM: *
Short Course on FBAT and PBAT
January 24-26, 2005, Harvard School of Public Health, Boston MA 02115
Please email completed form to Jennifer Fitts ([log in to unmask]
<mailto:[log in to unmask]>_). Do NOT send registration fee until
your acceptance has been confirmed. Once you have been accepted, the
full fee is required to hold your place.
*Name:*
* *
*Affiliation/Address:*
* *
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*Email Address:*
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*Position (e.g. PhD student in Epidemiology, Postdoc in Neurology, etc.):*
* *
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*Experience in Genetic Analysis, Family-Based Association Studies, etc.:*
* *
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*Previous Coursework in Statistics/Biostatistics:*
* *
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*Other Relevant Experience:*
* *
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*Software packages you are familiar with, INCLUDING FBAT and PBAT:*
* *
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*What do you hope to gain from attending this course?*
* *
* *
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*If you are interested in making a presentation on your work, please
attach an abstract.*
* *
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