Statistical Methods for Ordered Categorical Data
7-9 March
Presenters Kim Bolland and John Whitehead
Location Medical and Pharmaceutical Statistics Research Unit
The University of Reading, UK
Cost £900 (with discounts for early booking - see below)
Ordered categorical data arise from many clinical trials and epidemiological
studies. Commonly used scales include the Glasgow Outcome Scale in head injury,
where the five response categories are Good Recovery, Moderate Disability,
Severe Disability, Vegetative State and Death; the Barthel Index and modified
Rankin score in stroke; the Expanded Disability Status scale in multiple
sclerosis as well as various measures of quality of life. This course examines
the design and analysis of studies in which the primary response is of this
form.
Binary data are a special case of ordered categorical data and the course first
reviews the statistical methodology for binary data, with an emphasis on
logistic regression analysis. The generalisation from binary to ordinal data is
based on the assumption of proportional odds, and for a simple comparison of two
homogenous groups the method leads to the Mann-Whitney test. Linear modelling
and model checking are given prominence. Calculation and review of sample sizes
are examined, together with other design issues. Methods for the analysis of
repeated ordinal data based on the marginal model and on the subject-specific
model are presented and compared.
The course is extensively illustrated using examples drawn from the presenters'
consultancy experience. Many practical sessions are included, most of which
involve using SAS?.
Programme
* Review of binary data analysis
* The proportional odds model
* Fitting linear models using PROC LOGISTIC
* Model checking
* Alternative models
* Ordinal data and clinical trials
* Sample size and power
* Repeated ordinal data
Course fees
Students £540
Sponsors/Public
sector/academic £675
Other £765
For bookings made less than 6 weeks prior to commencement of the course the
fee is £900
The course fee includes all supporting documentation, refreshments and lunches.
Dinner is included on the first evening.
Cancellation
Registrations are transferable to another course or individual at any time,
otherwise cancelled course registration will incur the following charges:
11 - 20 days before the start of the course 50%
1 - 10 days before the start of the course 90%
course start date or later 100%.
We reserve the right to cancel any course without liability other than a refund
of the course fee.
For further information please contact
Barbara Dodds
MPS Research Unit
The University of Reading
PO Box 240, Earley Gate
Reading RG6 6FN, UK.
Tel: +44 118 378 6662
Fax: +44 118 975 3169
E-mail: [log in to unmask]
http://www.reading.ac.uk/mps
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