University of Newcastle upon Tyne, UK

Centre for Integrated Systems Biology of Ageing and Nutrition (CISBAN)

10 Post-doctoral and Research Technician posts (including postdoctoral
RA posts in Statistics, Mathematical modelling and Bioinformatics)

An exciting new research centre is being established, following a
major award (£6.4m) from BBSRC and EPSRC, to investigate the molecular
and cellular mechanisms responsible for ageing and the effects of
nutritional factors on these mechanisms. We are seeking outstanding
scientists for a wide range of posts who are attracted by the
challenge of working in an intensely multidisciplinary, world-class
research environment, with state-of-the-art facilities.

CISBAN will conduct integrated programmes of research linking
nutrition with mechanisms that contribute to ageing such as telomere
degradation, mitochondrial mutation, genome instability, oxidative
stress and the corresponding protection and repair systems. The
research will use mammalian cells in vitro and in vivo and yeast as
the principal experimental models. Extensive use will be made of
technologies such as expression arrays and proteomics, in addition to
specialised imaging and cell sorting procedures. The experimental work
will be closely complemented by extensive research in methods for data
integration, analysis, modelling and statistical
inference. Significant use will be made of robotics and advanced
engineering in developing and underpinning the research programmes.

CISBAN will conduct its research in association with the University of
Newcastle Institute for Ageing and Health, one of the leading
multidisciplinary institutes of its kind, providing exceptional
opportunities for interactions between basic and medical
sciences. Other partners include the Human Nutrition Research Centre,
North East Regional e-Science Centre, School of Computing Science,
School of Mathematics and Statistics, School of Chemical Engineering
and Advanced Materials, as well as relevant industries and an
extensive network of international collaborators.

10 New Post-doctoral positions are available immediately for
biologists in areas that include studies of cellular ageing in tissue
cultures, animal models and budding yeast, and for
mathematical-statistical-computing scientists in areas that include
mathematical modelling, development of new statistical inference
techniques, data integration and bioinformatics. Depending on previous
experience and the area of work, these appointments may be made at RA1
or RA2 level (RA1: £19,460 - £29,128; RA2: £27,116 - £35,883).

Informal enquiries for all posts may be made to Professor Tom
Kirkwood, CISBAN Director, e-mail: [log in to unmask] and
these will be referred as appropriate to programme leaders Professor
Thomas von Zglinicki, Professor David Lydall, and Dr Anil Wipat.

We also encourage scientists interested in applying for Fellowship or
other support in this area of research to contact Professor Kirkwood.

The closing date will be 15 July 2005, although late applications may
be submitted for consideration in further rounds of recruitment.

For further information, including how to apply, please visit our
vacancies web site http://www.ncl.ac.uk/vacancies or send a CV,
covering letter and completed employment record form to

Professor T Kirkwood,
Institute for Ageing and Health,
Henry Wellcome Laboratory for Biogerontology Research,
Newcastle General Hospital,
Newcastle upon Tyne NE4 6BE,

http://www.ncl.ac.uk/vacancies

Committed to Equal Opportunities

--
Darren Wilkinson Email: [log in to unmask]
                      WWW: http://www.staff.ncl.ac.uk/d.j.wilkinson/