Hi Richard.
One thing you may be able to do is create a difference map by subtracting the template from each subject using the ImCalc function in SPM. This would at least give you a decent idea of how well they match to the template. Hopefully you'll get a lot of zeros. :-)
This may be more of a qualitative approach though. However, perhaps getting an average of each difference map would give a measurement of how well each patient matches to the template. This is somewhat of a crude approach, but it should give you a start at least.
-John West
Imaging Analyst
Brain Imaging Lab
Dartmouth Medical School
|