Hello,
you could try to use the stereotactic (template) space as "meeting point"
for your two images, i. e. normalize them with affine steps only to the T2
(B0) and T1 template each. If you then invert the step taking your T1 to
the T1-template and apply this on your deformation matrix gained from
getting b0 to T2, you can use the resulting matrix to get your DTI (b0 and
weighted images) into the position of T1. It of course remains to be tested
in detail, if this is accurate enough.
Another way worth trying is segmentation of T1 into GM, WM and CSF and also
b0 (sometimes a calculated mean diffusivity image works better) and then
coregister your WM-maps from both modalities on eachother (or GM, depending
how well your segmentation works, sometimes even CSF is good as the
ventricles are well contrasted structures that can be coregistered). The
resulting transformation matrix could then be used for your initial whole
head image.
Philipp Sämann
Max-Planck-Institute of Psychiatry
Kraepelinstr. 2-10
80804 Munich
P. G. Saemann
Max-Planck-Institute of Psychiatry
NMR Research Group
Kraepelinsr. 2-10
80804 Munich
Mail: [log in to unmask]
Phone: 0049-89-30622-413 or -0 bleep 346
|