PBAT 2.0:
PBAT is an interactive software package that provides tools for the design
and the data analysis of family-based association studies. The new version
of PBAT contains the following features:
I) Power calculations for family-based association tests for continuous and
dichotomous traits
II) FBAT data analysis tools:
1.) Haplotype analysis (+sliding windows) and single SNP analysis
2.) Nuclear families and extended pedigrees
3.) Trait types: dichotomous, continuous, multivariate, longitudinal
and time-to-onset
4.) FBATs adjusted for covariates
5.) FBATs for main effects and gene-environment interactions
6.) Screening tools to handle the multiple comparison problem in
genome-wide association studies (conditional power estimates and Wald
p-values).
PBAT-Homepage:
http://www.biostat.harvard.edu/~clange/default.htm
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