GlaxoSmithKline and Imperial College London

Postdoctoral Researcher

GlaxoSmithKline (GSK), in collaboration with Imperial College London,
seeks to employ a postdoctoral researcher to develop statistical
methodology to be used in the analysis of clinical medical imaging
studies.  GSK is currently implementing a variety of clinical MRI studies
to evaluate patient populations and drug therapies.  One example would be
evaluating anti-cancer treatments via dynamic contrast MRI (DC-MRI) where
patients are imaged prior to treatment and then several times post
treatment in order to evaluate tumor response.  Scientific questions
include determining statistically significant changes in treatment groups
given all available patient data (from the level of voxels to treatment
groups) and characterizing sources of heterogeneity.  The problem will be
cast into a hierarchical Bayesian model, incorporating the spatial and
temporal dependencies from all levels of the study along with the current
knowledge and understanding of pharmacokinetics.  The postdoc will be
expected to establish collaborations with researchers both inside GSK and
with academic/research institutions in the UK.

Applicants should have a Ph.D. in Statistics, or relevant quantitative
field, with substantial experience in hierarchical Bayesian models applied
to spatio-temporal data.  Computing skills will be crucial as well as the
ability to communicate with scientists and researchers from a variety of
disciplines.  No previous experience with medical imaging is required.

The appointment is anticipated to start in September/October 2004 for a
period of 2 years.  The postdoc will be based at GlaxoSmithKline Research
& Development, Greenford, UK.

Starting salary will be in the range £21,368- £31,142 per annum, but may
be increased for more experienced candidates.  Additional funds for travel
and equipment will be provided by GSK.

Please contact Brandon Whitcher ([log in to unmask]) for more
information about this appointment.  Interested candidates are requested
to send their CV (including names of 3 referees) and examples of written
work (publications, technical reports, presentations, software code, etc.)
to Brandon Whitcher via email, or via GlaxoSmithKline, Greenford Road,
Greenford, Middlesex, UB6 0HE, UK.

Closing date: 27 August 2004