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Subject:

Re: allstat Digest - 19 Oct 2004 to 20 Oct 2004 (#2004-245)

From:

"Nelder, John A" <[log in to unmask]>

Reply-To:

Nelder, John A

Date:

Thu, 28 Oct 2004 10:40:59 +0100

Content-Type:

text/plain

Parts/Attachments:

Parts/Attachments

text/plain (1 lines)

Is your email address right? I have a note for you.J.Nelder.



	-----Original Message----- 

	From: A UK-based worldwide e-mail broadcast system mailing list on behalf of Automatic digest processor 

	Sent: Thu 10/21/2004 12:01 AM 

	To: Recipients of allstat digests 

	Cc: 

	Subject: allstat Digest - 19 Oct 2004 to 20 Oct 2004 (#2004-245)

	

	



	There are 7 messages totalling 220 lines in this issue.

	

	Topics of the day:

	

	  1. Statistician contract in Continental Europe

	  2. relative risk or odds ratio

	  3. Short Course in "R"

	  4. Question on Clustering (2)

	  5. REMINDER: RSS HIGHLANDS GROUP MEETING, 21/10/2004: John Norrie

	  6. Medical stat

	

	----------------------------------------------------------------------

	

	Date:    Wed, 20 Oct 2004 09:22:27 +0100

	From:    Mick Messing <[log in to unmask]>

	Subject: Statistician contract in Continental Europe

	

	Dear Allstaters

	

	My client is looking for an experienced Statistician to work in a

	Biostatistics department, which plays a key role in successful drug

	development by operating on an international level and contributing expert

	input to the drug development processes.

	

	Working closely with other statisticians and colleagues in drug development,

	especially data management and clinical research, biostatistics contributes

	to clinical trial activities within global projects.

	

	You will be responsible for the analysis and reporting of international

	clinical trials for regulatory submissions.

	

	The candidate must have a university degree in statistics or related subject

	and demonstrate a real interest in applied statistics, experience in SAS is

	required.

	

	This could either be a 6 or 12 months contract.

	

	Working in a very nice city with good connections to the UK.

	

	If you are interested please get in touch for further details.

	

	Kind regards

	

	Mick

	

	Mick Messing

	Biometrics Recruitment

	Key People Ltd

	Adelaide House, Adelaide Street,

	St. Albans, Herts AL3 5BE

	Tel: 01727 817 609 (Direct Number)

	Tel: 01727 811 634 (Switchboard)

	Fax: 01727 856 594

	Email: [log in to unmask]

	Website: http://www.keypeople.co.uk

	

	------------------------------

	

	Date:    Wed, 20 Oct 2004 13:01:10 +0000

	From:    Cathy Smith <[log in to unmask]>

	Subject: relative risk or odds ratio

	

	Dear All,

	

	If I have an option of using RR or OR, which one should I use?, Which one is

	more conservative?.

	

	Cathy

	

	_________________________________________________________________

	Get ready for school! Find articles, homework help and more in the Back to

	School Guide! http://special.msn.com/network/04backtoschool.armx

	

	------------------------------

	

	Date:    Wed, 20 Oct 2004 15:53:31 +0100

	From:    "Cutajar Bezzina, Audrienne" <[log in to unmask]>

	Subject: Short Course in "R"

	

	Apologies for cross-postings

	=20

	There are just few places remaining for the course "R".  R is

	increasingly becoming more popular in statistics, and it can be

	downloaded for free at http://cran.r-project.org/ =20

	=20

	The course runs from the 4th November 2004 to the 5th November 2004.

	Lunch will be provided, and there are also some bursaries which would

	enable the participant to attend the course free of charge.  Travel

	would also be reimbursed. =20

	=20

	For more information and a registration form, see:

	=20

	http://www.cas.lancs.ac.uk/short_courses/

	=20

	If you require further assistance, please contact

	=20

	Angela Mercer,

	Centre for Applied Statistics,

	Fylde College,

	Lancaster University,

	Lancaster,

	LA1 4YF, U.K.

	Tel: +44 (0)1524 593064.

	Fax: +44 (0)1524 593429.

	E-mail: [log in to unmask] <mailto:[log in to unmask]>=20

	=20

	

	------------------------------

	

	Date:    Wed, 20 Oct 2004 13:10:43 -0400

	From:    Regina Malina <[log in to unmask]>

	Subject: Question on Clustering

	

	Hi everyone,

	I have a question on variable selection when clustering.

	Should I remove highly-correlated variables when I perform clustering

	analysis? Does it make a difference if I do not? Is there a rule of thumb on

	how high the correlation should be in order to remove the variable?

	Thank you in advance. Regina

	

	------------------------------

	

	Date:    Wed, 20 Oct 2004 17:46:09 +0100

	From:    Claus Mayer <[log in to unmask]>

	Subject: REMINDER: RSS HIGHLANDS GROUP MEETING, 21/10/2004: John Norrie

	

	Dear all!

	The local RSS Highlands group will have it's first talk of the new season on Thursday, 21st of October (Details are given below). Please pass this information on to anybody who might be interested.

	

	Please also note that the webpage of the Highlands group has moved to:

	

	http://www.bioss.sari.ac.uk/RSSH/

	

	Regards,

	

	

	Claus-D. Mayer (local group secretary)

	

	-------------------------------------------------------------

	

	

	TITLE: "Randomised controlled trials (RCT) post EU Clinical Trials Directive - some issues for statisticians"

	

	SPEAKER: John Norrie, Director, Centre for Healthcare Randomised Trials (CHaRT), Health Services Research Unit, Aberdeen University

	

	VENUE: Room WB27,Health Services Research Unit, Polwarth Building,

	Foresterhill

	

	TIME: Thursday 21st October at 5pm (tea and coffee from 4.45pm)

	

	ABSTRACT:

	The EU Clinical Trials Directive, along with other legislation and guidance, has given an exacting regulatory, ethical, and legal environment in which RCT are now conducted. This talk will give some observations on statisticians roles, from the perspective of an experienced triallist and statistician who has been involved in many RCT, both large and small, both publicy funded and ommercial, before and after the implementation of EU/CTD. The talk will include discussions of risk assessment of trials, some aspects of regulatory advice on both the design and analysis of RCT (via the Points to Consider series), and some thoughts on statisticians involvement in the monitoring of RCT.

	

	--

	***********************************************************************************

	 Claus-D. Mayer                       | http://www.bioss.ac.uk

	 Biomathematics & Statistics Scotland | email: [log in to unmask]

	 Rowett Research Institute            | Telephone: +44 (0) 1224 716652

	 Aberdeen AB21 9SB, Scotland, UK.     | Fax: +44 (0) 1224 716608

	***********************************************************************************

	

	------------------------------

	

	Date:    Wed, 20 Oct 2004 14:14:14 -0400

	From:    Art Kendall <[log in to unmask]>

	Subject: Re: Question on Clustering

	

	A great deal depends on the substantive nature of your data and the

	reason you are clustering. Usually the variables are considered fairly

	independent.  In many contexts, it is common to use some form of factor

	scores. I know of no rule of thumb for what is "highly correlated".

	

	Clustering has a great deal of art to it.  You would want to try several

	approaches to see if the results are very different.  You might also use

	something like discriminant function analysis, remembering that tests as

	such lose most meaning when you use the same variables as those in the

	clustering.  Many of the parts of the listing from a package like SPSS

	can help give you insight into the different results.

	

	Art

	[log in to unmask]

	Social Research Consultants

	University Park, MD  USA

	(301) 864-5570

	

	

	Regina Malina wrote:

	

	>Hi everyone,

	>I have a question on variable selection when clustering.

	>Should I remove highly-correlated variables when I perform clustering

	>analysis? Does it make a difference if I do not? Is there a rule of thumb on

	>how high the correlation should be in order to remove the variable?

	>Thank you in advance. Regina

	>

	>

	>

	>

	

	------------------------------

	

	Date:    Wed, 20 Oct 2004 15:05:06 -0400

	From:    Isaac Dialsingh <[log in to unmask]>

	Subject: Re: Medical stat

	

	At the end of a contingency table in a medical paper, I am seeing two =

	Chi-square test statistics over 2000 vs 2001 for each category of the =

	column variable. Can anyone enlighten me as to what test is taking =

	place?

	

	Isaac Dialsingh

	

	------------------------------

	

	End of allstat Digest - 19 Oct 2004 to 20 Oct 2004 (#2004-245)

	**************************************************************

	



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