Dear all,
Apologies for cross-posting.
Please note that a new interface, "Pharmaco", is now
available at the WinBUGS Development web-site:
http://homepages.tesco.net/~creeping_death/
Pharmaco is an add-on interface to WinBUGS 1.4 that,
together with WBDiff, constitutes Version 2.0 of the
PKBugs software. Version 1.1 of PKBugs is still
required in order to perform simple "point-and-click"
specification of population PK models (i.e. without
using the BUGS language) but Pharmaco will allow
WinBUGS code generated using the "Print model" option
in PKBugs 1.1 to be run directly through WinBUGS 1.4.
This, of course, makes accessible to the population
PK analyst the various new features of WinBUGS 1.4,
such as the ability to run scripts in "batch-mode"
and the facility to specify the structural model in
terms of differential equations via WBDiff.
Some very minor alterations to the WinBUGS code
generated using PKBugs 1.1's "Print model" option are
required before that code can be run under the
Pharmaco interface in WinBUGS 1.4: the loop (over "i"
and "j") defining the "omega" matrix should be
replaced by a single line of code in which "omega" is
specified in terms of WinBUGS 1.4's matrix-valued
version of the "inverse(.)" function. For your
convenience I have prepared an upgrade patch for
PKBugs 1.1 that will incorporate into the software a
new menu option, namely "Export model", that will
make this modification for you, i.e. WinBUGS code
generated using the "Export model" option will run
under WinBUGS 1.4 without any alterations (as long as
the Pharmaco interface has been installed). (Note
that with the upgrade patch installed, "Export model"
should be used *instead of* "Print model".) The
PKBugs 1.1 upgrade patch is also available via the
WinBUGS Development web-site.
Best wishes,
Dave Lunn
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