Greetings SPMers,
I'm attempting to construct a paed T1 template.
At this stage I intend to use ONLY normal "controls", rather than "controls
and patients" because many of the patients have multiple areas of cortical
dysplasia.
There is a total 35 controls for use in template creation AND in any
subsequent analyses. Is it better to use a subset of these controls (say 16-
24) rather than the entire control set of 35?
A subset based template would reduce potential bias in later statistical
analyses. So the primary question is...what is the minimal number of
controls need to construct a representative template?
regards
Jason
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