KEELE UNIVERSITY
CENTRE FOR MEDICAL STATISTICS
SEMINAR SERIES on BIOSTATISTICS 2002/2003
NO 11: Wednesday, June 18th 2003, at 2:30 pm
Exploiting the potential of Bayesian methods in cluster randomised
trials
Simon Thompson
MRC Biostatistics Unit, Cambridge
The hierarchical data structure resulting from cluster randomised trials
can usefully be approached using Bayesian methods. These have certain
advantages over alternative methods of analysis such as summary
statistics methods, marginal models, and classical multilevel models. I
will show a number of applications of Bayesian methods in this area
including: sensitivity analysis to the assumed random effects
distribution, use of empirical evidence on intracluster correlation
coefficients (ICCs) as priors, analysis of absolute risk differences,
providing interval estimates for ICCs in complex situations, analysis of
multivariate outcomes, baseline adjustment in repeated cross-sectional
designs, and allowing for the imprecision of ICCs in sample size
calculations.
Venue: Room 2.22, Third Floor, MacKay Building, Keele University - All
welcome!!
http://www.keele.ac.uk/cwis.html
http://www.keele.ac.uk/depts/ma/news/#medstats
http://www.keele.ac.uk/university/campus/cgm.pdf
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Janet Drewery
Centre for Medical Statistics
Mathematics Department
MacKay Building
Keele University
Keele, Staffs ST5 5BG
Tel: (01782) 583269
Fax: (01782) 584268
E-mail: [log in to unmask]
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