Dear experts in SPM,
I am trying to apply the optimized protocol for VBM to
compare gray and white matter differences in a sample
of 40 controls and 34 patients. I have two questions
regarding the creation of a template:
Should I use part of the scans of my control sample or
should I rather do this from scans of an independent
healthy sample acquired with the same MRI protocol?
If using part of the scans of my sample is OK, then
should it be sufficient to use half of these scans
(i.e. 20)?
Thanks in advance for your attention
David
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Dr. David Bartrés Faz
Departament de Psiquiatria i Psicobiologia Clinica
Universitat de Barcelona
Postdoctoral researcher at INSERM ERM 205 'Imagierie Cerebrale en Psychiatrie'
SERVICE HOSPITALIER FREDERIC JOLIOT
4, Place du General Leclerc. 91401 Orsay Cedex, France
Tel: +33 1 69 86 77 19; Fax: +33 1 69 86 78 16
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