The next meeting of the Merseyside RSS Local Group will take place on
Thursday 21st November 2002 at 3pm.
Venue: Room 211, Department of Mathematical Sciences, Maths and
Oceanography Building, Peach Street, University of Liverpool,
Liverpool
APPROACHES TO DEALING WITH UNPLANNED PATIENT DROP-OUT IN CLINICAL
TRIALS
MIKE KENWARD (London School of Hygiene and Tropical Medicine)
Abstract:
Alternative approaches to completer-only and LOCF methods for handling
unplanned patient dropout are considered in the context of the trial aims
and underlying assumptions. Pattern-mixture and selection models, multiple
imputation methods, and weighted estimating equation methods are all
discussed. The importance for future development of sensitivity analysis
and the incorporation of additional information is stressed.
Tea will be served after the meting. All are welcome!
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