Hi FSL team,
To avoid the difficult task of separating CSF/skull, sienax normalizes brain
volume with respect to a standard. This approach is good for many
applications such as atrophy detection etc. However, if I do wish to have
intracranial volume as a denominator to normalise some other measurements,
what should I do then? Since CSF estimation may not be terribly robust, one
may want to use some methods other than just the sum of CSF, GM and WM. With
sienax, the scaling factor is worked out. If we have the ICV of the standard
brain that sienax uses in generating the scaling factor with, then we should
be able to work out ICV of an individual brain. Am I correct or not? Any
better method? If it is possible, then where do I find ICV of the standard
brain (MNI 152 brain?)? The mean of those 152 brains' ICV? Please give me
some clues?
Many thanks and regards,
Wei Wen
UNSW/Australia
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