We have done two in Lancaster one comparing im midazolam with im Ketamine
and another comparing oral midazolam with im Ketamine, both were published
in the Journal. Ketamine was superior despite the im dose of midazolam 0.4
mg/kg being the highest dose noted in the literature at the time. We have
stopped using midazolam for paediatric sedation now. We have done 458
ketamine procedures now using 2 to 2.5 mg/kg. Hope to publish the study of
500 cases next year.
Ray McGlone
Lancaster A&E
----- Original Message -----
From: "Julian Humphrey" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Tuesday, November 13, 2001 9:08 AM
Subject: Ketamine versus Midazolam for paediatric sedation
> Dear Colleagues,
>
> I am carrying out a systematic review of ketamine versus midazolam for
paediatric sedation as part of a course at the NHS Centre for Reviews and
Dissemination at the University of York.
>
> There are very few randomised controlled trials comparing the two methods
of paediatric sedation published in the literature.
>
> If anybody out there has unpublished trials or knows of any, I would be
very interested, if appropriate, in including the work in my review.
>
> Many thanks,
>
> Julian Humphrey
> A&E SpR
> Yorkshire Region
>
|