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From: <[log in to unmask]>
Subject: Flumazenil, Sedation and Fits
> Recently while reducing bilateral shoulder 'erecta' dislocations (don't
ask)
> under a bit of Midazolam and opiate I was challenged by a colleague as why
I
> was not wanting to use Flumazenil to simply reverse the Midaz as soon as
the
> procedure was over.
> I gave the standard 'Fit Risk' answer but was then asked to prove it....
> So does anyone have a reference/evidence for why we don't use it for
simply
> waking uncomplicated sedated patients up?
But we do use it for reversing sedation, that's what it was designed for! I
think Chris Kirke is right, in that the convulsant effect is principally a
concern in overdose patients, where flumazenil is not licensed. This precise
topic was covered within the last year on the LIST; I'm not sure of the
reference.
Adrian Fogarty
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