Hello Robert
Do you know which journal this reference comes from? Is it Lakartidningen or
is that another author? Is the article in English? It was one you suggested
in a posting
Disc herniation and sciatica; advances in our knowledge of the
pathophysiology and pain mechanisms.
Olmarker K, Rydevik B, Lakartidningen 1998;95: 5618-22
Cheers,
Anna.
Anna Lee
Principal,
Work Ready Industrial Athlete Centre
Physiotherapist & Occupational Health Consultant
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----- Original Message -----
From: "Robert Stålebring" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Friday, February 23, 2001 11:37 PM
Subject: SV: Disc and nerve root
Henry!
There is a lot of research on the subject. Try a medline search on the
author "Olmarker K". A swede with numerous papers published. I have this
summary from a swedish journal (however I think you prefer the summary in
english!?). I also picked up two references that I hope will suite you.
Summary:
"Sciatica has long been considered to be solely due to mechanical
deformation (compression) of a spinal nerve root by herniating disc tissue.
However, recent experimental findings have demonstrated that, even in the
absence of mechanical insult, nucleus pulposus- related substances may not
only induce significant structural and functional injury to the adjacent
nerve root, but also sensitise the nerve root, producing pain in the event
of subsequent root compression".
From:
Disc herniation and sciatica; advances in our knowledge of the
pathophysiology and pain mechanisms.
Olmarker K, Rydevik B, Lakartidningen 1998;95: 5618-22
Also look at:
Byrod G, Rydevik B, Nordborg C, Olmarker K. Early effects of nucleus
pulposus application on spinal nerve root morphology and function. Eur Spine
J. 1998;7(6):445-9.
Kikuchi S, Konno S, Kayama S, Sato K, Olmarker K. Increased resistance to
acute compression injury in chronically compressed spinal nerve roots. An
experimental study. Spine. 1996 Nov 15;21(22):2544-50.
Robert Stalebring
PT Sweden
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