Dear SPM ers,
we plan to compare a group of patients to healthy volunteers using voxel
based morphometry.
In the paper by Mummery et al. first a normalization is done and then
the individuals are segmented. Would it not be advantageous to:
a: normalize the whole brain
b: segment the non-normalized brain
c: using the paramters of (a) to normalize just the grey matter images.
I would expect a better segmentation before normalization !?
Any hints and opinions would be welcome.
Peter
Sabine
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