Dear SPMers,
We have recently completed an fMRI experiment with 9 subjects. All 9
subjects were realigned, normalized, smoothed, and entered into a first
level analysis p<0.05 corrected. The con*.img's were then entered into a
second level analysis for each condition (one sample t-test). With a
corrected p value p<0.05 we have no suprathreshold voxels (not surprising
with n=9) but with an uncorrected p value p<0.001 we can get an idea of
where acitvation is occuring. We took the uncorrected p value results and
used the volume button to identify voxels with the highest z score for
possible future study. (maybe SVC in a followup experiment).
My question is how to present the data that we have at this stage with the
greatest validity. Can we look at SVC data of the areas with highest z
scores, (which agree with our apriori hypotheses), should we do a fixed
effect analysis, or can we use the uncorrected p value data. Is there
anything else that I am missing?
Morgan Willson
In Vivo NMR Facility
Biomedical Engineering
University of Alberta
(780) 492 8098
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