Still, though, there would seem to exist a set of results which would
not be amenable to such an alternative explanation. That would be the
existence of an interaction of task and drug in regions at which there
is
no task effect at the drug factor level of "no drug". Isak, Jenny, any
thoughts?
Best,
Eric
The difficulty with this is that it is difficult to interpret a drug x task
interaction in a region of the brain that is not activated by the task in
the 'no-drug' or placebo condition and therefore this cannot circumvent the
problem of differential gain response in different regions on drug. However,
it is important to bear in mind that this should not invalidate the
technique, particularly if your effects are predicted and meaningful.
Yours,
Mitul
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