hi SPM
we would like to scan a patient with a large posterior brain lesion using fMRI
time-series. Looking at old correspondence from the list about this issue I have
found a number of relevant mails, but I have some more specific
questions relating to the normalization process and the template to
be used.
James Patterson's mail of 19/4/2000
http://www.mailbase.ac.uk/lists/spm/2000-04/0131.html
suggests that you could use the mean image of all the patients
scanned as a template. My question is this: if you have a single subject, could
you use the mean image from all the realigned scans of that subject?
What would you gain by this? Clearly this
would not help you put the brain in a Talairach space. On a more
general note, in a situation such as this what would be lost by NOT
normalizing at all - is it likely that your activations would be
spatially displaced? Is there another way to avoid this?
thanks -
Chris Summerfield
departament psiquiatria i psicobiologia clinica
universitat de barcelona
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