Dear Sheeba,
> Has anyone published a study by defining contrasts as GO-NOGO and NOGO-GO or
> of the similar type in event related design?
A quick search of MedLine using the phrase 'go no-go fMRI' shows at least
two relevant studies for you:
Konishi S, Nakajima K, Uchida I, Kikyo H, Kameyama M, Miyashita Y.
Common inhibitory mechanism in human inferior prefrontal cortex revealed by
event-related functional MRI.
Brain. 1999 May;122 ( Pt 5):981-91.
Konishi S, Nakajima K, Uchida I, Sekihara K, Miyashita Y.
No-go dominant brain activity in human inferior prefrontal cortex revealed
by functional magnetic resonance imaging.
Eur J Neurosci. 1998 Mar;10(3):1209-13.
I am sure there will be many more if you search MedLine more thoroughly.
> Also, what are limitations we define contrasts as GO-NOGO (1 -1) and
> NOGO-GO (-1 1)?
I'm not quite sure what you mean here? These contrasts will show those areas
where (event related) activity during GO trials is higher than NOGO trials,
or vice-versa.
best wishes,
Geraint
--
Dr. Geraint Rees
Wellcome Advanced Fellow, Lecturer,
Division of Biology 139-74, Institute of Neurology,
California Institute of Technology, University College London,
Pasadena CA 91125 London WC1N 3BG
voice 626-395-2880 020-7833-7472
fax 626-796-8876 020-7813-1420
web http://www.klab.caltech.edu/~geraint
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