Hello all.
I have been using SPM for VBM analysis, and would appreciate some input on a
couple of questions:
1. How can SPM best be used to compare a single subject to a group of
controls in order to establish the pattern of regional abnormalities? I
have tried using the two sample t-test, two groups, one scan per subject
model, with success, but was wondering if anyone had ideas about other
approaches using the software.
2. Can the SVC analysis be applied to any arbitrary contour defined by the
user (say, a hand-drawn outline of the frontal lobe), and how would one
accomplish this?
3. Can the SPM software generate a deformation map from the spatial
normalization, so that one could see the patterns of correction in different
regions?
Thanks
Howard Rosen, MD
Department of Neurology
University of California at San Francisco
350 Parnassus Avenue, Suite 501A, Box 1207
San Francisco, CA, 94143-1207
Ph: 415-476-6880
Fax: 415-476-4800
email: [log in to unmask]
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