Dear Stefan,
|if I do normalisation on anatomical and functional
|images, shall I coregister both modalities first or not?
If you want to use the anatomical image to overlay the functional
activations, then one way would be to coregister the T1-weighted
anatomical to the T2*-weighted EPI; normalise the EPI to the EPI
template; then normalise the T1 image using the same parameters.
If you are normalising the T1-weighted and T2*-weighted images separately,
to separate templates, then prior coregistration is irrelevant as the
normalisation parameters will be determined independently. But this
strategy might not be best, unless you have a specific reason.
best wishes,
Geraint
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Dr. Geraint Rees
Wellcome Advanced Fellow Lecturer
California Institute of Technology Institute of Neurology
Division of Biology 139-74 University College London
Pasadena 12 Queen Square
California 91125 London WC1N 3BG
voice (626) 395-2880 voice (171) 833-7472
fax (626) 796-8876 fax (171) 813-1420
http://www.klab.caltech.edu/~geraint [log in to unmask]
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