I am writing an analysis plan for a study that has a number of chemical
parameter primary endpoints (6)
The original sample size calculation did not take into acount multiplicity
of these endpoints.
If I adjust for this using the bonferoni method in the analysis, what
implications will this have on power of the study? Am i better off leaving
the significance level at 5% and advising that the results should be
carefully interpreted because of the multiplicity??
Thanks
_________________________________________________________________________
Get Your Private, Free E-mail from MSN Hotmail at http://www.hotmail.com.
|