ORDINARY MEETING ORGANIZED BY THE RESEARCH SECTION.
Wednesday 15 March, 5.00pm at the RSS (Tea 4.30pm)
MATTHEW STEPHENS AND PETER DONNELLY
(University of Oxford)
Inference in molecular population genetics
Summary: Modern molecular genetics generates extensive data
which document the genetic variation in natural populations.
Such data give rise to challenging statistical inference
problems both for the underlying evolutionary parameters
and for the demographic history of the population. This paper
reviews recently introduced MCMC and importance sampling
methods for approximating the relevant likelihood functions,
and a novel importance sampling algorithm is developed.
Comparison of these approaches suggests some general insights
for computationally intensive inference in problems with
high-dimensional missing data.
A postscript version of the paper is available at
http://www.maths.nott.ac.uk/personal/ild/rss/march15.ps
The meeting will take place at the Royal Statistical Society,
12 Errol Street, London EC1Y 8LX (nearest underground stations are
Old Street, Moorgate and Barbican). Tel: 0171 - 638 8998
For a hard copy of the paper please contact Val Evans
at the RSS ([log in to unmask]), stating your full postal address.
Ian Dryden
Hon Secretary, Research Section, RSS
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Research Section Web page:
http://www.maths.nott.ac.uk/personal/ild/rss/index.html
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