Dear Allstaters
I am reviewing a Clinical trial protocol and would like a reference to the
design used, a
"2-Stage Simon Design". My major concern is with the calculation of the
number of patients
needed for the trial which given the stated Response rates and error
values look to me to be low.
Thanks
Ken Ryder
Ken Ryder
Academic Oncology
3rd Floor
Thomas Guy House
Guy's Hospital
London SE1 9RT
Tel: 0207 955 5000 ext 3778
Fax: 0207 955 4812
|