Dear list members,
The paper "Optimal Two-Stage designs for Phase II Clinical Trials" (Simon,
Richard (1989) Controlled Clinical Trials 10,1-10) describes a procedure for
the planning of Phase II trials mainly in oncology. In the paper two designs
(for p1-p0=0.2 and p1-p0=0.15) were presented. In the planning of a current
project I will need the numbers for p1-p0=0.1 (especially p0=0.1 and
p1=0.2). Can anyone help directly or give me a hint who can help me to get
this information. Any help will be very appreciated.
Thank you in advance.
Martin Krauss
Biometric Center for Therapeutic Studies
Pettenkoferstr. 35
D-80336 Munich
Germany
Phone: +49-89-544 202-18
Fax: +49-89-544 202-14
e-mail: [log in to unmask]
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